Olanzapine is a medication used to treat schizophrenia. If taken for a long time, the body may develop a certain degree of dependence. Suddenly stopping the medication can cause withdrawal symptoms in most patients, manifested as the worsening of neurological symptoms, as well as sweating, insomnia, tremors, anxiety, nausea, vomiting, irritability, confusion, and hallucinations. Therefore, it is recommended to gradually reduce the dosage when discontinuing olanzapine.
Clinically, the dosage reduction of olanzapine generally needs to be done slowly. After reducing the dosage by 1/4 each time, it is necessary to maintain the new dosage for 1 to 4 weeks. The next step of dosage reduction can be carried out after observing the patient's mental state after the reduction.

If the patient's condition relapses during the dosage - reduction process, the original dosage should be resumed as soon as possible, and the next dosage reduction should be carried out after a re - evaluation by a professional doctor. If the condition relapses again during the second dosage reduction, it is generally not recommended to completely stop taking olanzapine. Instead, a low - dose long - term maintenance treatment can be considered.
Therefore, when discontinuing olanzapine, it is necessary to seek guidance from a neurologist after a full assessment of the patient's condition. Do not stop taking the medication on your own, as this may lead to a relapse or exacerbation of the condition.
