A small number of children develop rashes after taking ibuprofen orally or using ibuprofen suppositories due to their physical constitution. In this case, it is considered to be drug dermatitis. After this happens, first of all, avoid re - exposure to the suspected allergenic drug. Stop using ibuprofen and drink plenty of water to promote the metabolism of the drug. Secondly, use anti - histamine drugs such as cetirizine hydrochloride syrup and loratadine syrup. Apply calamine lotion, mometasone furoate, or halometasone externally to promote the disappearance of the rashes. When the condition is severe, glucocorticoids such as prednisone tablets or methylprednisolone tablets can be used. After application, the dosage needs to be gradually reduced under the guidance of a doctor, and anti - histamine drugs should be combined to consolidate the curative effect. Finally, the diet should be light. Avoid spicy and stimulating foods to prevent aggravating the rashes.