Ankylosing spondylitis is a disease of the immune system. Despite the current medical advancements, there is still no way to completely cure ankylosing spondylitis. However, patients don't need to be overly worried. For the majority of patients, the symptoms can be controlled and the prognosis can be improved through symptomatic treatment and appropriate functional exercises.

The treatment of ankylosing spondylitis mainly involves drug therapy. For example, non - steroidal anti - inflammatory drugs, sulfasalazine, glucocorticoids, and some immunosuppressants can help control the progression of the disease. In recent years, some newly developed biological agents, such as Yisaipu and Adalimumab, are quite expensive but have good effects and few side effects. They can also be used to treat ankylosing spondylitis.

For patients whose condition is poorly controlled and has progressed to the late stage, with joint and spinal ankylosis, limited mobility, and deformities, orthopedic surgery may be required for appropriate orthopedic correction to improve the patients' function. Most patients have an acceptable prognosis after regular treatment.