Low intracranial pressure headache occurs when the cerebrospinal fluid (CSF) pressure drops below 70 millimeters of mercury. The nocturnal electrical effect of the CSF weakens, causing the brain tissue to sink and shift. This leads to headache due to the stimulation of pain - sensitive structures at the base of the skull, as well as the dura mater, arteries, veins, and nerves. In the treatment of low intracranial pressure headache, treatment should be based on the cause. Usually, dehydration, uremia, meningitis, diabetic ketoacidosis, hyperventilation, hypotension, and severe systemic infectious diseases can all be the causes. Therefore, the causes need to be controlled, including controlling infections, replenishing body fluids, correcting dehydration, and treating the underlying diseases. Patients also need to strengthen self - care in daily life. They should reasonably arrange their rest time. It is important to note that patients with headaches should not stay up late for long periods. They should also avoid using their mobile phones for extended periods and stay away from negative emotional stimuli to keep a good mood.